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Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
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Morphological parameters associated with ruptured posterior communicating aneurysms.

Allen Ho1, Ning Lin1, Nareerat Charoenvimolphan2

  • 1Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America.

Plos One
|April 16, 2014
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Summary
This summary is machine-generated.

Smaller aneurysm volume, larger neck diameter, and shorter distance to the internal carotid artery (ICA) bifurcation are linked to posterior communicating artery (PCoA) aneurysm rupture. These factors aid in predicting rupture risk.

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Area of Science:

  • Neurosurgery
  • Radiology
  • Medical Imaging

Background:

  • Intracranial aneurysm rupture risk is linked to size, but morphological factors for specific locations remain unclear.
  • Posterior communicating artery (PCoA) aneurysms are common and require better rupture risk assessment.

Purpose of the Study:

  • To identify morphological characteristics associated with PCoA aneurysm rupture.
  • To evaluate the clinical applicability of these findings for predicting rupture risk.

Main Methods:

  • CT angiograms (CTAs) of 63 PCoA aneurysms (40 ruptured, 23 unruptured) were analyzed.
  • 3-D models were used to assess parameters: volume, aspect ratio, neck diameter, and distance to ICA bifurcation.
  • Univariate and multivariate logistic regression analyses were performed.

Main Results:

  • Smaller aneurysm volume, larger neck diameter, and shorter distance to the ICA bifurcation were significantly associated with rupture.
  • In subgroup analysis, larger neck diameter and shorter ICA bifurcation distance remained significant predictors.
  • Intracerebral hemorrhage correlated with smaller volume, larger height, smaller aneurysm angle, lateral projection, male sex, and lack of hypertension.

Conclusions:

  • Shorter ICA bifurcation to aneurysm distance is a novel, easily measurable predictor of PCoA aneurysm rupture.
  • These morphological parameters can enhance clinical evaluation and risk stratification for PCoA aneurysms.