Related Experiment Video
Updated: May 1, 2026
07:36
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
Published on: July 3, 2025
1.0K
Is Smoking a Risk Factor in Ocular Behçet Disease?
Ahmet Burak Bilgin1, Elif Betul Turkoglu1, Hatice Deniz Ilhan1
1a Akdeniz University, Faculty of Medicine, Department of Ophthalmology , Antalya , Turkey.
Ocular Immunology and Inflammation
|April 17, 2014
Summary
This study found that smoking does not negatively impact the prognosis or clinical outcomes of ocular Behçet disease. Smokers and non-smokers showed similar rates of uveitis recurrence and inflammation resolution.
Area of Science:
- Ophthalmology
- Rheumatology
- Clinical Medicine
Background:
- Behçet disease is a multisystem inflammatory disorder.
- Ocular involvement, particularly uveitis, significantly impacts patient prognosis.
- The role of smoking in the prognosis of Behçet uveitis remains unclear.
Purpose of the Study:
- To investigate the association between smoking and the prognosis of ocular Behçet disease.
- To compare clinical findings and outcomes in smokers versus non-smokers with Behçet uveitis.
Main Methods:
- Retrospective analysis of medical records from 202 patients with Behçet uveitis.
- Patients categorized into current smokers (n=72) and non-smokers (n=130).
- Comparison of uveitis localization, resolution time, recurrence rates, visual acuity, and cystoid macular edema (CME).
Main Results:
- No significant association found between smoking and the type of uveitis (anterior, posterior, panuveitis).
- Similar average times for inflammation resolution (48 vs. 51 days) and recurrence (8.6 vs. 9.1 months) between smokers and non-smokers.
- No statistically significant difference in the prevalence of cystoid macular edema (CME) between groups (25% vs. 32.3%, p=0.08).
Conclusions:
- Smoking does not appear to negatively influence the clinical course or prognosis of ocular Behçet disease.
- Findings suggest smoking status is not a significant prognostic factor for Behçet uveitis.
- Further research may elucidate complex interactions, but current data indicate no detrimental effect.
Related Concept Videos
01:24Chronic Obstructive Pulmonary Disease
3.0K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
3.0K
01:25Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
01:22Microbiome of the Eye
67
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
67
01:23Chronic Obstructive Pulmonary Disease I: Introduction
33
Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
33
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
5.0K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
5.0K
01:27Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K