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Updated: May 1, 2026

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
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Published on: May 4, 2016

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Parkin and PINK1: much more than mitophagy

Leslie A Scarffe1, Daniel A Stevens2, Valina L Dawson3

  • 1Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA.

Trends in Neurosciences
|April 17, 2014
PubMed
Summary

Parkinson's disease involves mitochondrial dysfunction. The genes PINK1 and parkin are crucial for mitochondrial health and quality control, extending beyond mitophagy.

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