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Equine interferons following exposure to equid herpesvirus-1 or -4
N Edington1, C G Bridges, L Griffiths
1Department of Veterinary Pathology, Royal Veterinary College, University of London.
Journal of Interferon Research
|August 1, 1989
Abstract:
When 23 ponies were infected with equid herpesvirus-1 or -4 (EHV-1 or EHV-4), nasal shedding of interferon (IFN) correlated closely with the duration of viral excretion. Equine interferon (EqIFN) was detected in the serum only from animals infected with the EHV-1 virus, and here high levels correlated with clinical symptoms of locomotor disorder and indicated a poor prognosis. Low levels of IFN were detected in explanted mononuclear cells from ponies infected with either virus.