Cerebellar granulocytic sarcoma: a case report.

Area of Science:

• Oncology
• Neuropathology
• Pediatric Hematology/Oncology

Background:

• Granulocytic sarcoma (GS) comprises immature granulocytic cells, often linked to acute myelogenous leukemia.
• Intraparenchymal cranial localization of GS, without broader invasion, is exceptionally rare.
• Cerebellar granulocytic sarcoma is particularly uncommon, with only 10 prior reported cases.

Purpose of the Study:

• To report an extremely rare case of intraparenchymal granulocytic sarcoma localized to the cerebellum.
• To contribute to the limited understanding of the mechanisms behind unusual cranial localizations of GS.

Main Methods:

• Case report of a 4-year-old boy.
• Clinical presentation and diagnostic findings were analyzed.

Main Results:

• A four-year-old boy presented with cerebellar granulocytic sarcoma.
• The tumor was intraparenchymal, without evidence of skull, meningeal, or bone marrow involvement.

Conclusions:

• This case highlights the rare intraparenchymal cranial manifestation of granulocytic sarcoma in a pediatric patient.
• Further research is needed to elucidate the pathogenesis of such rare presentations.