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Asymmetric facial skin viscoelasticity during climacteric aging
Gérald E Piérard1, Trinh Hermanns-Lê1, Ulysse Gaspard2
1Laboratory of Skin Bioengineering and Imaging, Department of Clinical Sciences, University of Liège, Belgium.
Menopause leads to asymmetric facial skin aging, specifically affecting biological elasticity and creep extension in post-menopausal women. This asymmetry is less pronounced in premenopausal women, highlighting changes during the menopausal transition.
Area of Science:
- Dermatology
- Gerontology
- Biophysics
Background:
- Climacteric skin aging impacts facial skin's biophysical properties.
- Facial skin aging is a significant concern during menopause.
Purpose of the Study:
- To evaluate the symmetrical involvement of facial cheeks in climacteric skin aging.
- To compare skin viscoelasticity between premenopausal and post-menopausal women.
Main Methods:
- Compared skin viscoelasticity on both cheeks of 84 women (36 premenopausal, 48 post-menopausal).
- Utilized a computerized suction device to measure skin unfolding, intrinsic distensibility, biological elasticity, and creep extension.
- Controlled for chronic sun exposure by selecting women with indoor occupational activities.
Main Results:
- Post-menopausal women exhibited asymmetry in biological elasticity and creep extension between cheeks.
- Premenopausal women showed less pronounced differences in these viscoelastic parameters.
Conclusions:
- Facial skin viscoelasticity becomes asymmetric after menopause.
- Future anti-aging and hormone replacement therapy studies should consider this facial asymmetry in menopausal women.
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