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Outer retinal structure after closed-globe blunt ocular trauma.

John A Flatter1, Robert F Cooper, Michael J Dubow

  • 1*Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin; †Department of Biomedical Engineering, Marquette University, Milwaukee, Wisconsin; ‡Department of Ophthalmology, New York Eye and Ear Infirmary, New York, New York; §Icahn School of Medicine at Mount Sinai, New York, New York; ¶Retina Consultants Ltd, Des Plaines, Illinois; and Departments of **Biophysics, and ††Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin.

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Summary
This summary is machine-generated.

Blunt ocular trauma can cause lasting outer retinal damage, affecting vision. Advanced imaging like adaptive optics scanning light ophthalmoscopy reveals photoreceptor disruption missed by standard methods.

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Trauma Research

Background:

  • Closed-globe blunt ocular trauma can lead to persistent visual deficits.
  • Understanding the underlying structural changes in the outer retina is crucial for patient management.

Purpose of the Study:

  • To evaluate outer retinal structural abnormalities in patients experiencing visual deficits after closed-globe blunt ocular trauma.
  • To compare the diagnostic capabilities of spectral domain optical coherence tomography and adaptive optics scanning light ophthalmoscopy in assessing trauma-induced retinal changes.

Main Methods:

  • Examined nine subjects with visual complaints following blunt ocular trauma, with follow-up ranging from 1 month to 6 years.
  • Utilized spectral domain optical coherence tomography (SD-OCT) to assess outer retinal architecture.
  • Employed adaptive optics scanning light ophthalmoscopy (AO-SLO) to analyze photoreceptor mosaic integrity.

Main Results:

  • Visual deficits included central scotomas and reduced visual acuity.
  • SD-OCT showed focal photoreceptor lesions, interdigitation zone attenuation, and outer segment band mottling.
  • AO-SLO revealed photoreceptor mosaic disruption in all subjects, with varying patterns of cone abnormalities.

Conclusions:

  • Persistent outer retinal disruption is observed in patients with visual complaints after blunt ocular trauma.
  • AO-SLO provides superior detail of photoreceptor structure compared to SD-OCT.
  • Multimodal imaging is valuable for diagnosing visual complaints post-trauma, warranting further longitudinal studies.