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Updated: May 1, 2026

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Approach to chronic cough.

Keya Rani Lahiri¹, Amruta Avinash Landge

¹Department of Pediatrics, Dr D Y Patil Medical College Hospital and Research Centre, Nerul, Navi Mumbai, 400706, Mumbai, Maharashtra, India.

Indian Journal of Pediatrics

|April 23, 2014

Summary

Chronic cough in children requires targeted treatment based on its cause, not just symptom relief. Avoid unnecessary antibiotics and over-the-counter syrups, focusing instead on accurate diagnosis for effective pediatric cough management.

Area of Science:

Pediatrics
Pulmonology
Clinical Medicine

Background:

Chronic cough significantly impacts children's quality of life.
Current treatments often involve symptomatic relief with over-the-counter syrups and antibiotics.
The diverse etiologies of chronic cough necessitate etiological diagnosis over symptomatic treatment.

Purpose of the Study:

To emphasize the importance of identifying the specific cause of chronic cough in children.
To guide appropriate diagnostic and therapeutic strategies for pediatric chronic cough.
To discourage the overuse of antibiotics and ineffective symptomatic treatments.

Main Methods:

Classification of chronic cough into specific and non-specific types.
Baseline investigations including chest radiography and peak flowmetry.

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Therapeutic trials with beta-2 agonists for airway hypersensitivity assessment in ambiguous cases.

Main Results:

Allergic conditions and tuberculosis are common causes of chronic cough in India.
Chest radiograph and peak flowmetry are essential baseline investigations.
Therapeutic trials can help diagnose asthma, but antibiotics should be avoided for asthma; tuberculosis requires treatment, not just a trial.

Conclusions:

Treatment for chronic cough in children must be etiology-directed.
Over-the-counter cough syrups are ineffective and should be avoided.
Referral to tertiary care is recommended for complicated or distressing cases, with close follow-up.