Sigmoid sinus occlusion infiltrated by inflammatory myofibroblastic tumor from mastoid
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Updated: May 1, 2026
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Jingye Wang1, Zhongwu Sun, Shengxia Zhuo
1Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Background:
Inflammatory myofibroblastic tumor (IMT) and some types of immunoglobulin (Ig) G4-related disease are often involved in the spectrum of inflammatory pseudotumor (IPT) and the concept of IgG4-related IPT/IMT has recently been proposed.
Methods:
A 38-year-old man complained of initial symptoms of blurred vision and headache.
Results:
A tumor was found in the right mastoid, which caused occlusion of the right sigmoid sinus and intracranial hypertension. A diagnosis of IMT with IgG4+ plasma cell infiltration was established by surgical, pathological, and immunohistochemistry findings. His symptoms were completely relieved after corticosteroid therapy and no recurrence was detected during 22 months of follow-up.
Conclusion:
A case with cerebral venous sinus infiltrated by IMTs in the head and neck has never been reported; corticosteroid therapy proved satisfactory in IMT with IgG4+ plasma cell infiltration.
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