Anti-gastroesophageal reflux surgery in infants with severe bronchopulmonary dysplasia

Area of Science:

• Pediatric Surgery
• Neonatology
• Pulmonology

Background:

• Gastroesophageal reflux is a common complication in infants with bronchopulmonary dysplasia (BPD).
• Reflux can significantly worsen respiratory status and lung disease severity in these vulnerable infants.
• Current management strategies for reflux in BPD infants are varied, with limited data on surgical interventions.

Purpose of the Study:

• To evaluate the safety and efficacy of anti-reflux surgery in infants diagnosed with severe bronchopulmonary dysplasia.
• To assess the impact of anti-reflux surgery on respiratory support requirements and clinical outcomes in this specific patient population.

Main Methods:

• Retrospective case series analysis of 22 infants with severe BPD who underwent anti-reflux surgery.
• Data collection included pre-operative and post-operative respiratory support (oxygen requirements, respiratory rate), and tolerance of early post-operative gastric feeding.

Main Results:

• Anti-reflux surgery was safely performed in all 22 infants with severe BPD.
• Early post-operative initiation of gastric feeds was well-tolerated.
• A modest reduction in the requirement for supplemental oxygen was observed post-surgery.
• A decrease in the median respiratory rate was noted following the surgical intervention.

Conclusions:

• Anti-reflux surgery is a feasible and safe option for managing gastroesophageal reflux in infants with severe BPD.
• The procedure may lead to improved respiratory parameters, including reduced oxygen dependence and respiratory rate.
• Early post-operative feeding is safe and well-tolerated, supporting early recovery.