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Updated: Apr 30, 2026
Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum
Guo-Jiang Mao1, Xiao-Bing Zhang, Xue-Lin Shi
1Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Collaborative Innovation Center for Molecular Engineering and Theranostics, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
Abstract:
A novel coumarin-based fluorescent probe, P-CM, for quantitative detection of nitroxyl (HNO) was developed. P-CM exhibits a selective response to HNO over other biological reductants and was also applied for quantitative detection of HNO in bovine serum with satisfactory results.
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