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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Published on: January 17, 2018

Partial empty sella syndrome: a case report and review.

P Aruna¹, B Sowjanya¹, P Amaresh Reddy²

¹Department of Biochemistry, Narayana Medical College, Nellore, AP India.

Indian Journal of Clinical Biochemistry : IJCB

|April 24, 2014

Summary

Primary empty sella syndrome affects the pituitary gland, often seen in middle-aged women. This condition, characterized by a flattened gland on MRI, has a prevalence of 8-35% in the general population.

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Area of Science:

Neurology
Endocrinology
Radiology

Background:

Empty sella syndrome involves damage or compression of the pituitary gland.
It is identified via Magnetic Resonance Imaging (MRI) scans that reveal a flattened gland.
The condition is often asymptomatic and discovered incidentally.

Observation:

Primary empty sella syndrome has a reported prevalence of 8-35% in the general population.
The incidence is higher in females, with a reported ratio of 5:1.
It is commonly observed in middle-aged women, frequently associated with obesity and hypertension.

Findings:

The pituitary gland appears shrunken or compressed within the sella turcica on MRI.
Cerebrospinal fluid may fill the enlarged sella, contributing to the 'empty' appearance.
Associated conditions like obesity and hypertension are noted in affected individuals.

Implications:

While often benign, understanding the prevalence and demographic associations is crucial for clinical awareness.
Further research may explore the underlying mechanisms and potential long-term effects.
Accurate diagnosis through MRI aids in differentiating from other sellar pathologies.