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Interventional Revascularization of Coronary Artery Lesions in Diabetic Patients; In-hospital and One Year Follow up

Mohammad Javad Zibaeenezhad1, Amir Aslani1, Alireza Moniri1

  • 1Cardiovascular Research Center, Shiraz University of Medical Science, Shiraz, IR Iran.

International Cardiovascular Research Journal
|April 24, 2014
PubMed

Insights

Drug-eluting stents show comparable safety and efficacy for single or two-vessel coronary artery disease in diabetic patients. This intervention can be a safe alternative to coronary artery bypass grafting.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Diabetology

Background:

  • Diabetes mellitus presents significant risks for micro- and macrovascular complications.
  • Limited research exists on the efficacy of coronary revascularization modalities in diabetic populations.
  • Diabetic patients face heightened risks from cardiovascular diseases.

Purpose of the Study:

  • To evaluate in-hospital complications and one-year clinical outcomes after percutaneous coronary intervention (PCI) in diabetic patients.
  • To compare the efficacy of single-vessel versus two-vessel stenting in diabetic individuals undergoing PCI.
  • To assess the safety and effectiveness of drug-eluting stents (DES) in diabetic patients with coronary artery disease.

Main Methods:

  • A study of 200 consecutive patients undergoing PCI between 2007 and 2009.
  • In-hospital complications and one-year clinical outcomes were meticulously recorded and analyzed.
  • Comparison of outcomes between diabetic and non-diabetic patients, and between single and two-vessel stenting.

Main Results:

  • No statistically significant difference in major adverse cardiovascular events was observed between diabetic and non-diabetic patients.
  • Outcomes for single-vessel stenting were comparable to two-vessel stenting in diabetic patients.
  • Drug-eluting stents demonstrated similar long-term and in-hospital outcomes for both one and two-vessel stenting in diabetic individuals.

Conclusions:

  • Percutaneous coronary intervention with drug-eluting stents is technically satisfactory and clinically safe for diabetic patients with single or two-vessel disease.
  • Drug-eluting stent implantation in diabetic patients can serve as a viable alternative to coronary artery bypass grafting.
  • PCI with DES offers a safe and effective revascularization strategy for diabetic patients with coronary artery lesions.
Abstract

Keywords:
Coronary Artery DiseaseDiabetes mellitusPercutaneous Coronary InterventionRevascularization

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