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Lozenges as delivery system for upper respiratory catarrh medication
Monika Bansal, Sachin K Singh, Monica Gulati1
1Department of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144 401, India. monicagulati14@gmail.com.
Recent Patents on Drug Delivery & Formulation
|April 25, 2014
Summary
Lozenges are a popular oral drug delivery system for cold and sore throat relief due to prolonged mucosal contact. This review explores lozenge formulations and their use for antitussive medications.
Area of Science:
- Pharmaceutical Sciences
- Drug Delivery Systems
Background:
- Lozenges are favored for upper respiratory tract disorders due to sustained drug contact with the naso-pharyngeal mucosa.
- Key benefits include maintaining mucosal moisture and enhancing the swallowing reflex.
Purpose of the Study:
- To review the multifaceted aspects of lozenges as an effective drug delivery system.
- To present the rationale for using lozenges for antitussive drug delivery.
Main Methods:
- Review of existing literature on lozenge formulations and drug delivery.
- Analysis of innovative technologies and ingredients used in lozenge development.
- Examination of patents related to antitussive lozenges.
Main Results:
- Lozenges offer prolonged drug contact time and local therapeutic effects in the upper respiratory tract.
- Numerous innovative approaches have improved lozenge formulations, including taste enhancement and modified release.
- Various antitussive agents have been successfully formulated into lozenges.
Conclusions:
- Lozenges represent an under-researched yet highly effective dosage form for respiratory ailments.
- Further research into novel lozenge technologies can optimize drug delivery for various conditions.
- Lozenges are a well-established and improvable platform for delivering antitussive medications.
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