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Related Concept Videos

Fatigue01:21

Fatigue

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Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
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Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
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Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...
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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
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Fatigue.

Jennifer Wright1, Kim M O'Connor1

  • 1Division of General Internal Medicine, Department of Internal Medicine, General Internal Medicine Centre, University of Washington, Box 354760, 4245 Roosevelt Way Northeast, Seattle, WA 98105, USA.

The Medical Clinics of North America
|April 25, 2014
PubMed
Summary
This summary is machine-generated.

This article guides primary care providers in managing fatigue, a common symptom with diverse causes. It emphasizes patient history, differential diagnosis, and strategies for cases where the cause remains elusive.

Keywords:
DepressionFatigueFerritinObstructive sleep apnea

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Area of Science:

  • Internal Medicine
  • General Practice

Background:

  • Fatigue is a prevalent symptom encountered in primary care settings.
  • Causes of fatigue vary widely, encompassing benign to severe conditions.

Purpose of the Study:

  • To provide guidance on the evaluation and management of patients presenting with fatigue.
  • To outline strategies for diagnosing and managing fatigue, particularly when the etiology is unclear.

Main Methods:

  • Review of key aspects of the patient's history of present illness.
  • Development of a differential diagnosis for fatigue.
  • Description of rational diagnostic evaluation for patients with non-diagnostic histories.
  • Guidance on management strategies for unexplained fatigue.

Main Results:

  • Patient history is crucial for guiding the evaluation of fatigue.
  • A systematic approach to differential diagnosis aids in identifying potential causes.
  • Rational diagnostic work-ups are essential, even with non-diagnostic histories.
  • Effective management strategies exist for patients with unexplained fatigue.

Conclusions:

  • Comprehensive patient history taking is fundamental for fatigue assessment.
  • A structured approach to diagnosis and management improves patient outcomes.
  • Management of fatigue requires tailored strategies, especially when a definitive diagnosis is not reached.