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Updated: Apr 30, 2026
08:43
An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
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[Small cell carcinoma in a vesical diverticulum: a case report]
Jun Nagai1, Nobuyuki Kondoh1, Keisuke Kajio2
1The Department of Urology, Kawanishi City Hospital・The Department of Urology, Kyowakai Kyoritsu Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|April 25, 2014
Summary
This case study details a rare instance of small cell carcinoma in a bladder diverticulum. Subsequent recurrence revealed urothelial carcinoma, necessitating partial cystectomy and chemotherapy.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Small cell carcinoma is a rare bladder cancer, with even rarer occurrences within vesical diverticula.
- Vesical diverticula can harbor unusual neoplastic processes, complicating diagnosis and treatment.
Observation:
- A 73-year-old woman presented with gross hematuria, found to have a non-papillary tumor in a vesical diverticulum.
- Initial histopathology of the transurethral resection of the tumor (TURBT) specimen confirmed small cell carcinoma.
- Recurrence within the diverticulum revealed urothelial carcinoma with microinvasion and venous invasion.
Findings:
- The patient underwent partial cystectomy with adequate margins for the recurrent tumor.
- Adjuvant chemotherapy with gemcitabine and cisplatin was administered for the urothelial carcinoma.
- This represents the fourth reported case of small cell carcinoma in a Japanese vesical diverticulum.
Implications:
- This case highlights the diagnostic and therapeutic challenges posed by rare tumors in vesical diverticula.
- It underscores the importance of thorough histopathological evaluation and consideration of secondary malignancies.
- Further research into the management of these rare entities is warranted to improve patient outcomes.
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