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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal stress predicts postpartum weight retention
Kara Whitaker1, Deborah Young-Hyman, Marlo Vernon
1University of South Carolina, 921 Assembly Street, Suite 318, Columbia, SC, 29208, USA, goodricm@email.sc.edu.
Postpartum weight retention (PPWR) is linked to stress. Higher depression and life stress in new mothers contribute to PPWR, impacting long-term maternal health.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Public Health
Background:
- Postpartum weight retention (PPWR) is a significant risk factor for overweight and obesity in women.
- Maternal stress is hypothesized to be a key factor influencing postpartum weight management.
- Understanding stress-related factors is crucial for developing effective interventions.
Purpose of the Study:
- To investigate the influence of specific parenting stress and life stress aspects on PPWR.
- To examine the temporal relationship between different stressors and weight retention in the first year postpartum.
- To identify key predictors of PPWR in new mothers.
Main Methods:
- Longitudinal study of 123 women from late pregnancy/early postpartum through the first year.
- Linear regression models assessed associations between parenting stress (isolation, attachment, depressive symptoms), life stress, and PPWR at 6 and 12 months.
- Covariates included gestational weight gain and race.
Main Results:
- Higher depression and life stress were significantly associated with greater PPWR during the first year postpartum.
- The influence of depression on PPWR decreased over time, while life stress became more significant.
- Unexpectedly, fewer attachment problems and less social isolation were linked to increased PPWR.
- Higher gestational weight gain and African American race were also significant predictors of PPWR.
Conclusions:
- Different types of stress predict postpartum weight retention in mothers during the first year.
- Parenting stress and concurrent life stress play distinct roles in PPWR.
- Interventions targeting specific maternal stressors may improve weight-related outcomes post-delivery.
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