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Simultaneous bilateral quadriceps tendons rupture in a patient with polyneuropathy

Atzmon Tsur, Arkady Galin, Norman Loberant

    The Israel Medical Association Journal : IMAJ
    |April 26, 2014
    PubMed
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    No abstract available in PubMed .

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    DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
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