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[Determination of thymidine phosphorylase in adenoma and cancer of the human prostate]
S Touffet1, S Samperez, P Jouan
1Centre Régional de Recherche en Endocrinologie, Faculté de Médecine et Pharmacie, Rennes.
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1989
Abstract:
The presence of thymidine phosphorylase was observed in healthy, adenomatous and tumoral prostatic cells. In healthy and adenomatous tissues the enzyme activity was recovered as a single peak after ion exchange chromatography on DEAE-Sephadex gel. On the contrary, two forms of thymidine phosphorylase were found in prostatic cancers, one of them, with high activity appeared consequently as a characteristic feature of prostatic tumoral cells.