Related Experiment Video

Updated: Apr 30, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

23.8K

Transient loss of consciousness in a patient with a Brugada like ECG

Belinda Sandler1, Steve Furniss1, Eric McWilliams1

  • 1East Sussex Healthcare NHS Trust, UK.

Clinics and Practice
|April 26, 2014
PubMed

Insights

Syncope in Brugada syndrome channelopathy patients has serious prognostic implications. This case highlights the importance of careful ECG review for diagnosing type 1 Brugada patterns, even when subtle.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Genetics

Background:

  • Brugada syndrome is an inherited cardiac channelopathy associated with an increased risk of sudden cardiac death.
  • Syncope in these patients necessitates thorough investigation due to significant prognostic implications.

Observation:

  • A 62-year-old male presented with transient loss of consciousness, initially suggestive of type 1 Brugada syndrome on ECG.
  • Investigations revealed a silent myocardial infarction and negative ajmaline testing and ventricular tachycardia stimulation.
  • Subsequent ECG review identified the type 1 Brugada pattern exclusively in lead V1.

Findings:

  • The case demonstrates a subtle presentation of type 1 Brugada syndrome, primarily localized to lead V1.
  • Negative provocative testing (ajmaline) and absence of inducible ventricular arrhythmias complicate the diagnostic picture.
  • The presence of a silent myocardial infarction adds complexity to the patient's cardiac status.

Implications:

  • This case underscores the critical need for meticulous ECG interpretation in diagnosing Brugada syndrome, especially subtle or localized patterns.
  • It highlights the challenges in risk stratification for Brugada syndrome when provocative testing is negative.
  • Consideration for implantable cardioverter defibrillator (ICD) in patients with syncope and suspected Brugada syndrome, even with ambiguous ECG findings, remains crucial.

Keywords:
Brugada pattern ECGsilent myocardial infarction.syncopetransient loss of consciousness

More Related Videos

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice09:20

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

Published on: July 5, 2021

2.7K
Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography09:23

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

Published on: November 24, 2016

13.0K

Related Concept Videos

Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
5.3K
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
788
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
18
Cardiac Action Potential01:30

Cardiac Action Potential

Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
11.8K
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
1.2K
Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
9.8K