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Updated: Apr 30, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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Allosteric sodium in class A GPCR signaling

Vsevolod Katritch1, Gustavo Fenalti1, Enrique E Abola1

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Trends in Biochemical Sciences
|April 29, 2014
PubMed

Keywords:
GPCR activationallosteric modulationbiased signalingconserved pocketsodium ionwater binding

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