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Initial clinical experience with a rate responsive pacemaker.

I Singer1, J Olash, A F Brennan

  • 1Cardiovascular Division, University of Louisville, School of Medicine, Kentucky 40202.

Pacing and Clinical Electrophysiology : PACE
|September 1, 1989
PubMed
Summary
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The Prism-CLR pacemaker, using evoked potential analysis for rate adjustment, showed appropriate rate increases in patients. Automatic output regulation was effective in most cases, suggesting its potential for rate-responsive pacing.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Pacemakers are crucial for managing bradyarrhythmias.
  • Rate-responsive pacing enhances physiological adaptation during activity.
  • Closed-loop systems offer advanced control in cardiac pacing.

Purpose of the Study:

  • To evaluate the efficacy of the Prism-CLR pacemaker.
  • To assess its closed-loop system for rate adjustment.
  • To examine the automatic output regulation feature.

Main Methods:

  • Implantation of the Prism-CLR pacemaker in five patients.
  • Monitoring of heart rate response to exercise and stress.
  • Evaluation of automatic output regulation for capture verification.

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Main Results:

  • All five patients demonstrated appropriate heart rate increases.
  • Automatic output regulation functioned correctly in three out of five patients.
  • Preliminary data indicate effectiveness for rate-responsive pacing.

Conclusions:

  • The Prism-CLR pacemaker shows promise for rate-responsive pacing.
  • The automatic output regulation algorithm may require further refinement.
  • Further studies are warranted to optimize performance.