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Updated: Apr 30, 2026

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
[Infant botulism after honey exposure]
1Unité de pédiatrie générale, hôpital universitaire des enfants Reine-Fabiola, université Libre de Bruxelles, Bruxelles, Belgique.
Abstract:
Infant botulism is a rare neuroparalytic disease caused by the neurotoxin of Clostridium botulinum. Initial clinical features are constipation, poor feeding, descending hypotonia, drooling, irritability, weak crying and cranial nerve dysfunctions. We describe the clinical progression and the epidemiological investigation carried out in a 3-month-old infant. Better knowledge of the disease should allow faster diagnosis and adequate management. We emphasize the risks associated with honey exposure in children less than one year old and that honey should not be fed to infants under 12 months of age.
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