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A search for calcium-channel activators in the verapamil series
M N Romanelli1, F Gualtieri, R Mannhold
1Dipartimento di Scienze Farmaceutiche, Università di Firenze, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|May 1, 1989
Abstract:
A new series of phenylalkylamines related to Verapamil have been synthesized and their Ca2+-modulating activity on rabbit aorta and on guinea-pig heart were evaluated. The compounds display only a moderate Ca2+-antagonistic activity; none of them showed any Ca2+-agonistic effect.