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Updated: Apr 30, 2026

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
[DMEK in corneal endothelial disorders: first Swiss consecutive series]
1Augenzentrum Klinik Pallas, Olten, Schweiz.
Purpose:
The aim of this study was to analyse clinical and functional results after Descemet membrane endothelial keratoplasty (DMEK) as preferred technique in patients with Fuchs dystrophy and endothelial decompensation in a consecutive series.
History And Signs:
In 12 eyes of 11 patients with Fuchs dystrophy or postoperative corneal decompensation a Descemet membrane endothelial keratoplasty as sole technique was indicated. All eyes were pseudophakic. Mean preoperative visual acuity was 0.25. Corneal stromal edema was observed since 18 months in mean.
Therapy And Outcome:
There were neither postoperative complications nor graft loss due to preparation. Mean follow-up time was 7 months. Stromal edema vanished within 4 weeks in mean. Postoperative visual acuity improved in all cases to 0.6 in mean. Neither immune reaction nor endophthalmitis nor primary graft failure were observed so far. Endothelial cell loss was 20% in mean.
Conclusion:
Descemet membrane endothelial keratoplasty seems to be a promising procedure. Long-term follow-up will show the real value of this exciting technique.

