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Updated: Apr 30, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
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CLARA: an integrated clinical research administration system.

Jiang Bian1, Mengjun Xie2, William Hogan3

  • 1Division of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA Research Systems, Information Technology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Journal of the American Medical Informatics Association : JAMIA
|April 30, 2014
PubMed
Summary

The Clinical Research Administration (CLARA) platform streamlines human subject research administration. This web-based system improves efficiency for submissions, reviews, and approvals, aiding regulatory compliance.

Keywords:
Clinical and Translational Science Awardclinical research administrationclinical research workflowelectronic IRB

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Area of Science:

  • Health Informatics
  • Clinical Research Administration
  • Regulatory Science

Background:

  • Human subject research administration is complex, involving multiple regulatory entities.
  • The efficiency of research administration significantly impacts clinical research conduct and management.

Purpose of the Study:

  • To report on the development and capabilities of the Clinical Research Administration (CLARA) platform.
  • To demonstrate how CLARA can streamline administrative tasks in clinical research.

Main Methods:

  • Development of a comprehensive, web-based platform named CLARA.
  • Integration of submission, review, and approval processes for investigators and review committees.
  • Inclusion of tools for budgeting, contracting, and participant scheduling.

Main Results:

  • CLARA provides a single, integrated platform for research administrative tasks.
  • The system streamlines submissions, reviews, and approvals.
  • CLARA offers tools to manage various clinical research activities beyond initial approvals.

Conclusions:

  • The CLARA platform enhances the efficiency and management of human subject research administration.
  • CLARA assists investigators in meeting regulatory requirements.
  • This integrated system supports the overall conduct of clinical research.