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Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

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Lymphoma mimics obstructive sialadenitis: three cases.

Amir Laviv¹, Aliyah R Sohani², Maria J Troulis³

¹Chief Resident, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons

|May 1, 2014

Summary

This summary is machine-generated.

Obstructive sialadenitis, often caused by infection or stones, can rarely be a sign of low-grade follicular lymphoma. Early consideration of neoplasm is crucial for persistent salivary gland obstruction symptoms.

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Area of Science:

Oral and Maxillofacial Surgery
Oncology
Pathology

Background:

Obstructive sialadenitis is a frequent salivary gland condition.
Common causes include infections, sialolithiasis, duct stricture, and mucous plugs.
Differential diagnosis should also encompass dehydration, trauma, scarring, and neoplasm.

Observation:

A review of 591 obstructive sialadenitis cases was conducted.
The cases were referred to Massachusetts General Hospital's Oral and Maxillofacial Surgery Service between 2009 and 2012.
Three patients presented with obstruction due to low-grade follicular lymphoma.

Findings:

Low-grade follicular lymphoma can manifest as obstructive sialadenitis.
Neoplasm should be suspected in persistent cases unresponsive to standard treatments.
This highlights a rare but significant cause of salivary gland obstruction.

Implications:

Clinicians should consider lymphoma in the differential diagnosis of obstructive sialadenitis.
Prompt diagnosis and treatment of underlying neoplasm are vital for patient outcomes.
This finding expands the known causes of salivary gland obstruction.