Digitally Guided Frontal Sinus Fracture Fixation: A Point-of-Care "In-House" Biomodel Protocol with
Manuel Tousidonis1,2,3, Saad Khayat1, Cristina Maza-Muela1,2
1Department of Oral and Maxillofacial Surgery, Gregorio Marañon University Hospital, 28007 Madrid, Spain.
Journal of Clinical Medicine
|March 14, 2026
Summary
This study presents a novel digital workflow for treating comminuted frontal sinus fractures. Combining 3D biomodeling and cyanoacrylate adhesive with microplates offers improved fragment stabilization and aesthetic restoration.
Area of Science:
- Craniofacial surgery
- Digital imaging and modeling
- Biomaterials science
Background:
- Comminuted frontal sinus fractures present challenges in achieving stable osteosynthesis due to small, irregular fragments.
- Aesthetic deformity is a common sequela of untreated or poorly managed anterior frontal sinus wall fractures.
- Conventional fixation methods may be insufficient for complex fragment configurations.
Purpose of the Study:
- To describe a point-of-care digital workflow for managing isolated comminuted anterior frontal sinus wall fractures.
- To evaluate the efficacy of 3D planning and printing combined with cyanoacrylate-assisted fixation.
- To assess the restoration of forehead contour and fragment stability.
Main Methods:
- A patient with a comminuted frontal sinus fracture underwent a digital workflow including 3D biomodel-guided planning and extracorporeal reconstruction.
- Modified N-butyl-2-cyanoacrylate adhesive (Glubran 2) was used as an adjunct fixation method.
- Titanium microplates were employed for additional reinforcement of the reconstructed anterior wall.
Main Results:
- The 3D-printed biomodel facilitated precise visualization and anatomical reassembly of fracture fragments.
- The cyanoacrylate adhesive aided in maintaining fragment reduction, particularly where screw purchase was limited.
- The combined approach resulted in immediate restoration of forehead contour, satisfactory alignment, and an uneventful postoperative recovery.
Conclusions:
- Point-of-care 3D biomodeling integrated with cyanoacrylate adhesive is a feasible adjunct to microplate fixation for comminuted frontal sinus fractures.
- This digital workflow enhances fragment handling and improves aesthetic outcomes in complex cases.
- The technique preserves sinonasal drainage and avoids the need for sinus obliteration.
Keywords:
3D-printed templateaesthetic contour restorationbiomodel-guided reductioncyanoacrylate-assisted fixationextracorporeal reductionfrontal sinus fracturein-house manufacturingpoint-of-care 3D printingsurgical adhesivetitanium microplates

