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Updated: Apr 30, 2026

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System
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Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem

Ismail Ismailoglu1, Qiuying Chen2, Melissa Popowski1

  • 1Laboratory of Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.

Developmental Biology
|May 1, 2014
PubMed

Keywords:
AMP kinaseEmbryonic stem cellsGlycolysisHuntington׳s DiseaseLC-MS/MSMetabolismMetabolomicsMitochondriaMitochondrial bioenergeticsMitochondrial respirationOxygen consumptionUntargeted metabolite profiling

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