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Updated: Apr 30, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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Catalytic asymmetric synthesis of 8-oxabicyclooctanes by intermolecular [5+2] pyrylium cycloadditions

Michael R Witten1, Eric N Jacobsen

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford St., Cambridge, MA 02138 (USA).

Angewandte Chemie (International Ed. in English)
|May 1, 2014
PubMed

Keywords:
asymmetric catalysisconformational analysiscycloadditionhydrogen bondsorganocatalysis

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