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[Therapy-induced lindane concentration in breast milk].
E Senger1, I Menzel, H Holzmann
1Abteilung I des Zentrums der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität, Frankfurt/Main.
Dermatosen in Beruf Und Umwelt. Occupation and Environment
|September 1, 1989
Summary
Lindane (gamma-hexachlorcyclohexane) treatment for scabies in mothers can significantly increase lindane concentration in breast milk. This finding raises concerns about infant exposure to this neurotoxic pesticide through breastfeeding.
Area of Science:
- Toxicology
- Environmental Health
- Pediatrics
Background:
- Lindane (gamma-hexachlorcyclohexane) is a pesticide used to treat scabies.
- Neurotoxic effects in infants treated with lindane have been reported, leading to controversy regarding its use in early infancy.
- Previous literature lacks data on lindane concentrations in human milk following maternal scabies treatment.
Observation:
- This study monitored lindane levels in breast milk of a mother treated for scabies.
- Elevated lindane concentrations were detected in the mother's milk post-treatment.
Findings:
- Lindane levels in breast milk showed a 30-fold increase after three days of treatment.
- A further increase to a 66-fold elevation was observed after an additional day of treatment, compared to average levels (0.03 ppm, milk-fat).
Implications:
- Maternal use of lindane for scabies poses a risk of infant exposure to elevated levels of this neurotoxic pesticide via breast milk.
- The findings necessitate a re-evaluation of lindane's safety for breastfeeding mothers and highlight the need for alternative scabies therapies.
- Further research into safer treatment options for scabies in breastfeeding mothers is warranted to protect infant health.