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Updated: Apr 30, 2026

Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Patulin in apple juices: Incidence and likely intake in an Indian population
Neha Saxena1, Premendra D Dwivedi, Kausar M Ansari
1a Food Toxicology Division, Indian Institute of Toxicology Research , MG Marg , PB No. 80 , Lucknow 226001 , India.
Abstract:
Fifty samples of apple juices were investigated for patulin levels using HPLC with UV detection. It was found that 38 (76? samples contained no detectable patulin (LOD = 7.5 µg l(-1)), but some samples had high patulin levels (845 µg l(-1)) compared to other branded mixed juices (21-70 µg l(-1)) and apple juices procured from local vendors (191 µg l(-1)). The survey provides evidence of a need to educate the apple-juice industry in the use of good quality apples for juice production. In addition, the levels of patulin found showed a saturation of the provisional maximum tolerable daily intake (PMTDI) based on intake figures in terms of an average and 90th percentile of 27-60% and 107-190%, respectively, in different age groups. This monitoring study may help in formulating guidelines for patulin levels, which are not yet implemented by Prevention of Food Adulteration (PFA) Act of India.

