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Related Concept Videos

Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Endocarditis I: Introduction01:25

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis IV: Nursing Management01:29

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Rheumatic Heart Disease I: Introduction01:23

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
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Related Experiment Video

Updated: Apr 30, 2026

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
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Osteomyelitis in Kawasaki disease.

Satya Prakash Singh1, Nasir Husain Ansari, Yashwant Singh Tanwar

  • 1Department of Orthopaedics, PGIMER, Dr RML Hospital, Room no-302, New Delhi, 110001, India, spsingh_5@yahoo.co.in.

Indian Journal of Pediatrics
|May 3, 2014
PubMed
Summary

Kawasaki disease (KD) and osteomyelitis share overlapping symptoms, suggesting a potential link. While IVIG treated KD symptoms, osteomyelitis required long-term antibiotics.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Rheumatology

Background:

  • Kawasaki disease (KD) is an acute febrile illness affecting young children.
  • Osteomyelitis is a bone infection, often caused by bacteria like Staphylococcus aureus.
  • Differentiating KD from other febrile illnesses can be challenging.

Observation:

  • A pediatric case presented with symptoms mimicking Kawasaki disease.
  • The patient was diagnosed with osteomyelitis, a bone infection.
  • Initial treatment with intravenous immunoglobulin (IVIG) effectively managed KD-like symptoms.

Findings:

  • Osteomyelitis required a prolonged course of antibiotics for resolution.
  • The co-occurrence of KD symptoms and osteomyelitis was noted.

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  • This clinical overlap suggests a potential relationship between KD and S. aureus pyogenic osteomyelitis.

    • Implications:

    • The findings highlight the importance of considering osteomyelitis in children with KD-like symptoms.
    • Further research may elucidate the underlying mechanisms connecting KD and bacterial bone infections.
    • This case emphasizes the need for comprehensive diagnostic approaches in pediatric febrile illnesses.