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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Psychoneuroimmunology: Diabetes and Cancer01:19

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

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Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Related Experiment Video

Updated: Apr 30, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

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Psoriasis and comorbidities: links and risks.

Catherine Ni1, Melvin W Chiu1

  • 1Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA.

Clinical, Cosmetic and Investigational Dermatology
|May 3, 2014
PubMed
Summary
This summary is machine-generated.

Psoriasis patients have higher rates of serious health conditions like heart disease and diabetes. Early screening and treatment for these comorbidities are crucial for effective psoriasis management.

Keywords:
cardiovascularmetabolic syndrome

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Last Updated: Apr 30, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Area of Science:

  • Dermatology
  • Internal Medicine
  • Epidemiology

Background:

  • Psoriasis is a chronic inflammatory skin condition affecting 2% of the global population.
  • Comorbidities in psoriasis have gained significant research attention.
  • Understanding these links is vital for holistic patient care.

Purpose of the Study:

  • To review epidemiological data on psoriasis comorbidities.
  • To explore pathophysiological links between psoriasis and other diseases.
  • To discuss therapeutic strategies for managing psoriasis comorbidities.

Main Methods:

  • Literature review of studies on psoriasis comorbidities.
  • Analysis of epidemiological evidence.
  • Synthesis of pathophysiological and therapeutic information.

Main Results:

  • Psoriasis is associated with increased prevalence of cardiovascular disease, obesity, diabetes, hypertension, dyslipidemia, metabolic syndrome, nonalcoholic fatty liver disease, cancer, anxiety, depression, and inflammatory bowel disease.
  • These conditions occur more frequently in psoriasis patients than in the general population.
  • Significant pathophysiological commonalities exist.

Conclusions:

  • Comprehensive screening for comorbidities is essential in psoriasis patients.
  • Integrated treatment approaches are necessary for optimal management.
  • Addressing comorbidities improves overall health outcomes for individuals with psoriasis.