[Studies on the effect of bleomycin on hair growth dynamics in rats]

In investigations on Wistar rats aged 4-5 weeks it was found that intraperitoneal administration of Bleomycin in doses from 0.015 to 0.045 mg/100 g of body weight caused disturbances of hair growth. Initially hair loss had a telogenic mechanism, and after higher doses administered for longer time periods it changed to poorly evidenced alopecia with a dystrophic-telogenic pathological mechanism, without clinical signs of fur thinning.