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Updated: Apr 30, 2026
05:15
Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
Published on: October 20, 2019
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Anterior chamber keratinous horn
Mojtaba Abrishami1, Fariba Ghassemi1, Zakieh Vahedian1
1Ocular Oncology and Retina and Vitreous Service, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Summary
A 14-year-old boy experienced eye masses diagnosed as keratinous material. Surgical removal was successful, with no recurrence observed during follow-up.
Area of Science:
- Ophthalmology
- Dermatology
- Histopathology
Background:
- Iris lesions can present with varied etiologies.
- Early diagnosis and treatment are crucial for preserving visual function.
Observation:
- A 14-year-old male presented with a 6-month history of white, fluffy, and vegetative hornlike masses on the iris periphery.
- Ultrasound biomicroscopy identified an echogenic mass at the iris root and angle without posterior segment involvement.
Findings:
- Histopathological examination of the excised mass confirmed the presence of keratinous material.
- The diagnosis was consistent with a cutaneous choristoma or similar keratin-producing lesion.
Implications:
- This case highlights an unusual presentation of keratinous material within the iris.
- Complete excision appears to be an effective treatment, preventing recurrence of iris masses.
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