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Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
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Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance

Published on: March 7, 2025

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Helicobacter pylori infection in Omani children

Siham Al-Sinani1, Sharef W Sharef, Khalid Al-Naamani

  • 1Gastroenterology Unit, Department of Child Health, Sultan Qaboos University Hospital, Muscat, Oman.

Helicobacter
|May 7, 2014
PubMed

Insights

Helicobacter pylori (H. pylori) infection prevalence in Omani children is 25%. The study found no significant link between H. pylori and recurrent abdominal pain, gender, or anemia in this population.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Public Health

Background:

  • Helicobacter pylori (H. pylori) is the most common chronic bacterial infection globally.
  • Data on H. pylori prevalence in Omani pediatric populations is currently lacking.

Purpose of the Study:

  • To determine the prevalence of H. pylori infection in Omani children using histology.
  • To investigate potential associations between H. pylori infection and clinical factors in children.

Main Methods:

  • Retrospective analysis of gastric biopsy results from children over a three-year period.
  • Comparison of H. pylori-positive and negative groups based on age, gender, indication for endoscopy, abdominal pain history, and anemia.

Main Results:

  • The overall prevalence of biopsy-proven H. pylori infection was 25% among 112 pediatric patients.
  • Prevalence increased with age, peaking between 5 and 10 years (33%), with a significant rise from <5 years (7%) (p=0.010).
  • No significant associations were found between H. pylori infection and recurrent abdominal pain, gender, or anemia.

Conclusions:

  • This study provides the first histology-based prevalence data for H. pylori infection in Omani children (25%).
  • The prevalence is lower than in many regional and Arab countries.
  • H. pylori infection in Omani children showed no significant association with recurrent abdominal pain, gender, or anemia.
Abstract

Keywords:
H. pyloriOmanchildrengastritis

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