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Related Experiment Video

Updated: Apr 30, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Alopecia caused by isoniazid.

Ramakant Dixit1, Danish Qureshi1, Sunil Mathur1

  • 1Departments of Respiratory Medicine and Pharmacology and Experimental Therapeutics, J. L. N. Medical College, Ajmer, Rajasthan, India.

Journal of Pharmacology & Pharmacotherapeutics
|May 7, 2014
PubMed
Summary
This summary is machine-generated.

Drug-induced alopecia is rare during anti-tuberculosis therapy. This case highlights isoniazid as a potential cause, with hair loss reversing after treatment cessation in a pediatric patient.

Keywords:
Alopeciadrugsisoniazid

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Area of Science:

  • Pharmacology
  • Dermatology
  • Pediatrics

Background:

  • Drug-induced alopecia is a recognized side effect, primarily associated with anti-mitotic agents.
  • Alopecia during anti-tuberculosis therapy is uncommon, with few documented cases linked to specific drugs.

Observation:

  • A 10-year-old male child developed alopecia during anti-tuberculosis treatment.
  • The hair loss was specifically associated with isoniazid therapy.

Findings:

  • This report documents an additional case of isoniazid-induced alopecia.
  • The alopecia was fully reversible upon discontinuation of isoniazid, suggesting a direct causal link.

Implications:

  • Isoniazid should be considered as a potential cause of alopecia in pediatric patients undergoing anti-tuberculosis treatment.
  • Understanding the mechanisms of drug-induced alopecia is crucial for patient management and therapeutic choices.