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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
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Related Experiment Video

Updated: Apr 30, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
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Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

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Retinal detachment.

David Steel1

  • 1Sunderland Eye Infirmary, Sunderland, UK.

BMJ Clinical Evidence
|May 9, 2014
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates surgical interventions for rhegmatogenous retinal detachment (RRD). It assesses the effectiveness and safety of various treatments, including vitrectomy and scleral buckling, for RRD and related complications.

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Evidence-Based Medicine

Background:

  • Rhegmatogenous retinal detachment (RRD) is a common condition caused by a retinal break, leading to fluid ingress and retinal separation.
  • RRD affects approximately 1 in 10,000 individuals annually, necessitating effective treatment strategies.

Purpose of the Study:

  • To systematically review the effects of different surgical interventions for rhegmatogenous retinal detachment.
  • To evaluate interventions for treating proliferative vitreoretinopathy, a complication of RRD or its prior treatment.

Main Methods:

  • Conducted a systematic literature review searching major databases (Medline, Embase, Cochrane Library) up to September 2013.
  • Included studies on surgical interventions for RRD and proliferative vitreoretinopathy.
  • Incorporated safety alerts from regulatory agencies like the FDA and MHRA.

Main Results:

  • Identified 14 studies meeting the inclusion criteria for the systematic review.
  • Performed a GRADE evaluation to assess the quality of evidence for various interventions.
  • Synthesized information on the effectiveness and safety of multiple treatment options.

Conclusions:

  • The review presents data on the effectiveness and safety of interventions for RRD.
  • Evaluated treatments include corticosteroids, chemotherapy agents, pneumatic retinopexy, scleral buckling, gas tamponade, silicone oil tamponade, and vitrectomy.
  • Provides evidence to inform clinical decision-making for RRD management.