ANK3 gene expression in bipolar disorder and schizophrenia

Katrine Verena Wirgenes1, Martin Tesli1, Elin Inderhaug1

  • 1Katrine Verena Wirgenes, MD, Martin Tesli, MD, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Elin Inderhaug, BSc, Lavinia Athanasiu, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Division of Mental Health & Addiction and Department of Medical Genetics, Oslo University Hospital, Oslo, Norway; Ingrid Agartz, MD, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo; Division of Mental Health and Addiction, Oslo University Hospital; and Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway; Ingrid Melle, MD, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital; Timothy Hughes, PhD, Department of Medical Genetics, Oslo University Hospital; Ole Andreas Andreassen, MD, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Division of Mental Health and Addiction, Oslo University Hospital; Srdjan Djurovic, PhD, NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, and Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.

Summary

Ankyrin-3 (ANK3) gene expression in blood is elevated in bipolar disorder and schizophrenia. This suggests ANK3 mRNA may serve as a valuable biomarker for understanding these psychotic disorders.

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