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Related Experiment Videos

Blood modeling using polystyrene microspheres.

E Fukada1, G V Seaman, D Liepsch

  • 1Hal B. Wallis Research Facility, Eisenhower Medical Center, Rancho Mirage, California 92270.

Biorheology
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

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Researchers created a blood-mimicking fluid using polystyrene microspheres. Adding dextran and calcium ions induced non-Newtonian behavior, similar to blood rheology.

Area of Science:

  • Materials Science
  • Biophysics
  • Fluid Dynamics

Background:

  • Understanding the rheological properties of suspensions is crucial for various applications, including biomimicry.
  • Polystyrene microspheres are commonly used model systems in colloid science.

Purpose of the Study:

  • To investigate the rheological properties of aqueous polystyrene microsphere suspensions.
  • To explore methods for inducing non-Newtonian behavior in these suspensions to mimic human blood.

Main Methods:

  • Determined steady flow viscosity and dynamic viscoelasticity of microsphere suspensions.
  • Introduced dextran and calcium chloride to alter suspension properties.

Main Results:

  • Suspensions exhibited Newtonian behavior up to 32% particle concentration.

Related Experiment Videos

  • Dextran and calcium ions induced non-Newtonian behavior at 12% concentration, mimicking blood.
  • Particle aggregation was observed due to cooperative effects of dextran and calcium ions.

    • Conclusions:

    • Aqueous suspensions of uniform polystyrene microspheres can be engineered to mimic blood rheology.
    • Controlling surface charge via calcium ions is key to achieving blood-like non-Newtonian behavior.