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Updated: Apr 30, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Clinical performance of a highly porous beta-TCP as the grafting material for maxillary sinus augmentation
Raphael Bettach1, Bernard Guillaume, Silvio Taschieri
1*Adjunct Associate Professor, New York University College of Dentistry, Department of Implant Dentistry, New York, NY; Private Practice, Gretz-Armainvilliers, France. †President, French College of Implantology; Private Practice, Paris, France. ‡Academic Researcher, Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milano, Italy; Chief of the Section of Endodontics and Implant Surgery, Dental Clinic, IRCCS Istituto Ortopedico Galeazzi, Milano, Italy. §Academic Researcher, Director of the Research Center for Oral Health, Department of Biomedical, Surgical, and Dental Sciences, Università degli Studi di Milano, Milano, Italy; IRCCS Istituto Ortopedico Galeazzi, Milano, Italy.
Background:
Beta-tricalcium phosphate (β-TCP) is a synthetic bone substitute having high porosity and fast resorption. This retrospective study aimed at evaluating the effectiveness of an highly macroporous β-TCP for maxillary sinus floor augmentation.
Methods:
Twenty-seven consecutive patients (17 woman/10 men, mean age: 59.7 years) in 2 clinics underwent maxillary sinus augmentation by lateral approach using β-TCP as grafting material. Implant survival, prosthesis success, periimplant bone loss, oral hygiene level, soft tissue condition, complication occurrence, and patient satisfaction were assessed.
Results:
Thirty-one sinuses were successfully augmented. Sixty implants were placed. No sinus membrane perforations occurred. The mean follow-up after grafting was 39.3 ± 8.7 months (range, 22-52 months), and it was 30.5 ± 8.1 months (range, 15-43 months) after implant loading. No implants were lost. After 1 year of loading, marginal bone loss averaged -0.88 ± 0.46 mm (n = 54 implants). Mean full-mouth plaque and bleeding scores were 11.5% ± 4.8% and 3.5% ± 2.8%, respectively. No biological or mechanical complications were recorded. Patient satisfaction was very high.
Conclusion:
Despite limited sample size and follow-up duration, highly macroporous β-TCP proved a valuable bone substitute for sinus augmentation, even when used alone.
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