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Identifying environmental antigens that activate myelin-specific T cells

Brian D Stadinski1, Eric S Huseby1

  • 1Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

Trends in Immunology
|May 14, 2014
PubMed

Human genetic and environmental factors underlie susceptibility to the T cell-mediated autoimmune disease, multiple sclerosis (MS). How the environment influences the pathogenesis of MS has been difficult to parse. A recent paper in Cell shows that environmental antigens that activate myelin-specific T cells can be identified with unprecedented accuracy.

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