Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

259
Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
259
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.7K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

842
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
842
Hand hygiene01:23

Hand hygiene

5.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suicide rates in the UK Armed Forces, compared with the general workforce and merchant shipping during peacetime years since 1900.

BMJ military health·2023
Same author

Role of Kidney Stones in Renal Pelvis Flow.

Journal of biomechanical engineering·2022
Same author

Rectal foreign body removal: increasing incidence and cost to the NHS.

Annals of the Royal College of Surgeons of England·2021
Same author

Forgotten fatalities: British military, mining and maritime accidents since 1900.

Occupational medicine (Oxford, England)·2021
Same author

A temperature model for laser lithotripsy.

World journal of urology·2020
Same author

A Systematic Review and Meta-analysis of Paediatric Inflammatory Bowel Disease Incidence and Prevalence Across Europe.

Journal of Crohn's & colitis·2020

Related Experiment Video

Updated: Apr 29, 2026

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
09:31

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Published on: February 27, 2018

14.4K

Cephalosporin prophylaxis for total hip replacement.

M A Ritter, M F Conway, E A Stringer

    Orthopedics
    |May 15, 2014
    PubMed
    Summary

    Cefamandole demonstrated superior tissue penetration for total hip replacement antibiotic prophylaxis compared to cephalothin. Optimal dosing strategies are crucial for effective surgical site infection prevention.

    Area of Science:

    • Orthopedic Surgery
    • Infectious Disease
    • Pharmacology

    Background:

    • Assessing the efficacy of antibiotic prophylaxis is crucial for preventing surgical site infections in total hip replacement (THR).
    • Recommended antibiotic regimens require validation for adequate drug concentration at the surgical site.

    Discussion:

    • Cefamandole achieved higher and more consistent antibiotic levels across multiple tissue types, including bone, compared to cephalothin.
    • The study highlights the importance of drug penetration in deep tissues for effective prophylaxis.

    Key Insights:

    • Cefamandole offers better tissue penetration than cephalothin in total hip replacement surgery.
    • Optimized timing for antibiotic administration, including a second dose one hour post-initial, is recommended.

    More Related Videos

    The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
    09:51

    The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

    Published on: September 7, 2022

    3.0K
    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
    10:35

    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

    Published on: December 3, 2017

    12.6K

    Related Experiment Videos

    Last Updated: Apr 29, 2026

    Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
    09:31

    Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

    Published on: February 27, 2018

    14.4K
    The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
    09:51

    The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

    Published on: September 7, 2022

    3.0K
    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
    10:35

    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

    Published on: December 3, 2017

    12.6K
  • Cephalothin requires maximum dosage due to its limited tissue penetration.

    • Outlook:

    • Further research could explore alternative antibiotics or novel drug delivery systems for enhanced prophylaxis.
    • Establishing standardized protocols for antibiotic prophylaxis in THR based on drug penetration data is warranted.