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Related Experiment Video

Updated: Apr 29, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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Prostate cancer screening.

John W Ragsdale1, Brian Halstater1, Viviana Martinez-Bianchi1

  • 1Department of Community and Family Medicine, Duke Family Medicine Center, Duke University, 2100 Erwin Drive, Durham, NC 27710, USA.

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|May 17, 2014
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Summary
This summary is machine-generated.

Universal prostate cancer screening is not advised due to harms outweighing benefits. Shared decision-making is crucial for patients interested in prostate-specific antigen testing.

Keywords:
DREDigital rectal examinationPSAProstate cancerProstate-specific antigenScreening

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Area of Science:

  • Urology
  • Preventive Medicine
  • Public Health

Background:

  • Universal screening for prostate cancer (Pca) using prostate-specific antigen (PSA) testing is controversial.
  • Current guidelines often do not recommend routine Pca screening due to potential harms like overdiagnosis and overtreatment.
  • The balance between screening benefits and risks requires careful consideration.

Purpose of the Study:

  • To evaluate the current recommendations and rationale against universal prostate cancer screening.
  • To emphasize the importance of shared decision-making in Pca screening discussions.
  • To explore how new healthcare models can support preventive service delivery.

Main Methods:

  • Review of current literature and guidelines on prostate cancer screening.
  • Analysis of the risks (overdiagnosis, overtreatment) versus benefits of PSA testing.
  • Discussion of shared decision-making principles in clinical practice.

Main Results:

  • Universal PSA-based screening for prostate cancer is not recommended.
  • The harms associated with overdiagnosis and overtreatment are considered to outweigh the benefits.
  • Shared decision-making is essential for patients considering Pca screening.

Conclusions:

  • A paradigm shift is needed in Pca screening, focusing on risks over undetected cancer.
  • Physicians should engage in shared decision-making with patients regarding Pca screening preferences and risk profiles.
  • Healthcare models, including those influenced by the Patient Protection and Affordable Care Act, aim to facilitate preventive care.