Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

7.5K
7.5K
DNA as a Genetic Template02:05

DNA as a Genetic Template

22.2K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
22.2K
DNA Microarrays02:34

DNA Microarrays

16.8K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
16.8K
DNA Topoisomerases02:02

DNA Topoisomerases

32.2K
Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
32.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cultivation of Chlorella sorokiniana with Simulated Flue Gas and Utilization of the Biomass as Fertilizer.

Applied biochemistry and biotechnology·2026
Same author

Bidirectional Perceptual Multimodal Interaction Network Based on Contrastive Learning for Breast Cancer pCR Prediction.

Tomography (Ann Arbor, Mich.)·2026
Same author

Structural characterization, lipid-lowering activity, and emulsifying properties of polysaccharides derived from wheat pericarp via Ganoderma lucidum solid-state fermentation.

Food research international (Ottawa, Ont.)·2026
Same author

Impact of hospital process reengineering on door-to-needle time for intravenous thrombolysis in acute ischemic stroke (PROMISE-CHINA): a multicenter prospective pre-post quasi-experimental study.

Frontiers in neurology·2026
Same author

Scalable Nickel Electrode Enabled by Water-Oxygen Corrosion for Kilogram-Scale Electrosynthesis of 2,5-Furandicarboxylic Acid.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

TRACE: reconstructing fragmented microbial landscapes for high-resolution antimicrobial resistance surveillance.

Frontiers in microbiology·2026
Same journal

Upcycling food processing byproducts via advanced yeast fermentation.

Current opinion in biotechnology·2026
Same journal

Microbial C1 assimilation pathways for chemical synthesis: from native metabolism to synthetic design.

Current opinion in biotechnology·2026
Same journal

Medicinal plants fermentation: current knowledge and perspectives.

Current opinion in biotechnology·2026
Same journal

Fermented foods: lessons learned from metagenomics.

Current opinion in biotechnology·2026
Same journal

Microfluidic platforms for the transient transfection of mammalian cells: recent developments and challenges.

Current opinion in biotechnology·2026
Same journal

Harvesting insights from recent advances in yeast genomics for predictable and precision wine fermentation.

Current opinion in biotechnology·2026
See all related articles

Related Experiment Video

Updated: Apr 29, 2026

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

12.7K

Nanomaterials and nanoclusters based on DNA modulation.

Yan Fu1, Xian Wang1, Jinli Zhang1

  • 1Key Laboratory of Systems Bioengineering MOE, Key Laboratory for Green Chemical Technology MOE, Tianjin University, Tianjin 300072, People's Republic of China.

Current Opinion in Biotechnology
|May 17, 2014
PubMed
Summary
This summary is machine-generated.

DNA

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

14.0K
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

10.5K

Related Experiment Videos

Last Updated: Apr 29, 2026

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

12.7K
Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

14.0K
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
09:17

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Published on: March 5, 2019

10.5K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Supramolecular Chemistry

Background:

  • DNA possesses inherent chirality and functional groups for metal ion coordination.
  • DNA self-assembly forms diverse structures like G-quadruplexes and i-motifs.
  • DNA's coordination and self-assembly properties enable novel material construction.

Purpose of the Study:

  • To review recent advancements in DNA-modulated nano/subnano materials.
  • To highlight DNA biotemplating for nanomaterial synthesis.
  • To explore DNA's role in creating switchable nanomachines and enantioselective platforms.

Main Methods:

  • Literature review of DNA-based biotemplating and material modulation.
  • Analysis of DNA's coordination chemistry with transition metals.
  • Discussion of DNA self-assembly strategies for nanomaterial design.

Main Results:

  • DNA biotemplating is an effective strategy for nanomaterial construction.
  • DNA's inherent properties facilitate the design of switchable nanomaterials.
  • DNA-modulated approaches offer environmentally benign routes to nanostructures.

Conclusions:

  • DNA-based modulation is a promising avenue for creating advanced nanomaterials.
  • Future research focuses on DNA-guided synthesis of nanomachines and enantioselective systems.
  • DNA offers a versatile platform for developing sustainable nanotechnology solutions.