Effect of Postbreeding Intramuscular Administration of Deslorelin Acetate on Plasma LH and Progesterone
Satoshi Kino1, Takeshi Osawa2, Shuji Mizuno3
1Laboratory of Theriogenology, Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Iwate 020-8550, Japan ; Laboratory of Theriogenology, Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Iwate 020-8550, Japan.
Abstract:
To clarify effect of postbreeding intramuscular administration of deslorelin on mares, plasma LH and progesterone concentrations and conception rate were evaluated. In Experiment 1, deslorelin, buserelin, or a placebo was administered on day 9 (day 0=day of last breeding or AI). Plasma samples were collected daily from days 6 to 15, and additional samples were taken after treatment. There was a significant increase in hormonal concentrations after deslorelin treatment. In Experiment 2, deslorelin or placebo was injected on day 9. There was no difference in conception rates at days 15 and 30 between the two groups. While a single postbreeding treatment of deslorelin increased peripheral LH and progesterone concentrations, it may not affect the conception rate in mares.
