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Optic disc neovascularization in dominant exudative vitreoretinopathy
1Moorfields Eye Hospital, London, England.
Retina (Philadelphia, Pa.)
|January 1, 1989
Summary
Dominant exudative vitreoretinopathy (DEVR) is an inherited retinal vascular disorder. A case report highlights optic disc neovascularization as a previously unreported DEVR manifestation.
Area of Science:
- Ophthalmology
- Genetics
- Retinal Vascular Diseases
Background:
- Dominant exudative vitreoretinopathy (DEVR) is an inherited retinal vascular disorder.
- Characterized by peripheral retinal neovascularization, tractional retinal detachment, subretinal exudation, and vitreous fibrosis.
- Milder forms may present with capillary nonperfusion and straightened retinal vessels in asymptomatic individuals.
Observation:
- A 15-year-old patient presented with optic disc neovascularization.
- This finding is not previously reported in association with DEVR.
- Angiographic evidence confirmed DEVR in successive generations.
Findings:
- Optic disc neovascularization represents a novel manifestation of DEVR.
- The study reviews findings in both mild and advanced DEVR.
- Pathogenesis of capillary nonperfusion in DEVR is discussed.
Implications:
- Expands the clinical spectrum of DEVR.
- Highlights the importance of comprehensive retinal examination in suspected DEVR cases.
- Contributes to understanding the pathogenesis of inherited retinal vascular disorders.