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[Recent developments in the biochemistry of hirudins]
1Institut für Pharmakologie und Toxikologie, Medizinischen Akademie Erfurt.
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1989
Abstract:
The paper reviews both the isolation methods of native hirudin and the manufacturing process of recombinant hirudins as well as the primary structures of the different hirudin variants. Furthermore, the review presents an evaluation of current studies in the mechanisms of the antithrombin action of hirudin.