Related Experiment Video
Updated: Apr 29, 2026

03:30
Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
Published on: October 25, 2024
2.7K
Evidence-based outcomes for mesh-based surgery for pelvic organ prolapse
Jayadev R Mettu1, Marc Colaco, Gopal H Badlani
1Department of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Current Opinion in Urology
|May 20, 2014
Summary
Synthetic mesh improves surgical outcomes for pelvic organ prolapse (POP) compared to native tissue repair, despite a risk of mesh exposure. Patient goals and physician guidance are key to treatment decisions.
Area of Science:
- Urogynecology
- Pelvic Floor Surgery
Background:
- Pelvic organ prolapse (POP) is a common condition affecting women's quality of life.
- Synthetic mesh use in POP surgery is controversial due to potential complications.
Purpose of the Study:
- To review evidence-based outcomes and complications of synthetic mesh for POP surgery.
- To evaluate mesh efficacy compared to native tissue repair.
Main Methods:
- Retrospective review of 18 recent studies (last 5 years).
- Included prospective randomized or quasi-randomized controlled trials.
- Analyzed Cochrane reviews and meta-analyses.
Main Results:
- Synthetic mesh shows superior anatomical and subjective cure rates versus native tissue repair.
- Recurrence rates are significantly lower with mesh-based surgery.
- Mesh exposure occurred in 11.4% of patients, with 6.8% requiring surgical intervention.
Conclusions:
- Mesh significantly improves anatomical outcomes in POP repair.
- Mesh complications, like exposure, can be mitigated through training and patient selection.
- Further material development is recommended over reverting to tissue-based repair.

